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pentobarbital will reduce the level or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Powerful or average CYP3A4 inducers may well enhance charge of diazepam elimination; consequently, efficacy of diazepam could be reduced.The use of barbiturates as sedatives in the postoperative sur